Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.60 |
| ▸ | HRH1 | P35367 | 1/20 | 0.57 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.57 |
| ▸ | PER2 | O15055 | 1/20 | 0.56 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.56 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12858712 | 0.86 | KDM4E (0.61) | DNM1PER2CRY1CRY2RAB9A | |
| SCHEMBL21093044 | 0.80 | RAD52 (0.53) | DNM1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL30645225 | 0.80 | DNM1 (0.61) | DNM1RAB9AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL21093026 | 0.80 | RAD52 (0.53) | DNM1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL21093337 | 0.80 | RAD52 (0.53) | DNM1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL21093057 | 0.80 | RAD52 (0.53) | DNM1KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL14889275 | 0.78 | BACE1 (1.00) | BACE1DNM1PER2 | |
| SCHEMBL12858681 | 0.77 | DNM1 (0.67) | BACE1DNM1KDM4EALDH1A1 | |
| SCHEMBL14578715 | 0.77 | BACE1 (0.81) | BACE1DNM1HRH1HRH4PER2 | |
| SCHEMBL408965 | 0.75 | DNM1 (1.00) | BACE1DNM1HRH1HRH4PER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10314816-B2 | Antimicrobial compounds, compositions and methods of use thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10314816-B2 | Antimicrobial compounds, compositions and methods of use thereof | CLPP, ATP5ME, PCNA | BACE1 3790/4885DNM1 290/4885HRH1 2867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.