Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25634887 | 0.82 | GPR3 (0.48) | GPR3CYP1A2CYP2C19KDM4EATM | |
| SCHEMBL12092119 | 0.82 | GPR3 (0.48) | GPR3CYP1A2CYP2C19KDM4EATM | |
| SCHEMBL12270320 | 0.79 | PTPN2 (0.35) | KDM4ECHEK1CDK5CDK5R1ALDH1A1 | |
| SCHEMBL13089300 | 0.76 | — | — | |
| SCHEMBL25634885 | 0.76 | GPR3 (0.42) | GPR3CYP1A2CYP2C19KDM4EATM | |
| SCHEMBL12270433 | 0.76 | HPRT1 (0.41) | CYP1A2KDM4EATML3MBTL1CHEK1 | |
| SCHEMBL12270507 | 0.76 | CHEK1 (0.33) | KDM4ECHEK1CDK5CDK5R1ALDH1A1 | |
| SCHEMBL19914101 | 0.74 | CYP1A2 (0.47) | GPR3CYP1A2CYP2C19KDM4EATM | |
| SCHEMBL25635341 | 0.71 | GPR3 (0.37) | GPR3CYP1A2CYP2C19KDM4EATM | |
| SCHEMBL17809837 | 0.71 | KDM4E (0.41) | GPR3CYP1A2CYP2C19KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | KEIO UNIVERSITY (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028739-A1 | TRI-SUBSTITUTED AROMATIC COMPOUND | AHR, AR, ARNT | GPR3 20/4885CYP1A2 436/4885CYP2C19 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.