Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220610 | 0.86 | TMEM97 (0.57) | TMEM97MRGPRX4 | |
| SCHEMBL13685883 | 0.84 | TMEM97 (0.53) | MAOBALDH1A1TMEM97MRGPRX4 | |
| SCHEMBL17369723 | 0.84 | TMEM97 (0.47) | MAOBMAOATMEM97MRGPRX4 | |
| SCHEMBL13546027 | 0.81 | TMEM97 (0.46) | TMEM97 | |
| SCHEMBL12861014 | 0.80 | MAOB (0.59) | MAOBALDH1A1MAOATMEM97 | |
| SCHEMBL6665880 | 0.80 | MAOB (0.58) | MAOBALDH1A1MAOAMRGPRX4 | |
| SCHEMBL13546034 | 0.79 | TMEM97 (0.44) | MAOBMAOATMEM97MRGPRX4 | |
| SCHEMBL13525145 | 0.79 | TMEM97 (0.44) | MAOBALDH1A1MAOATMEM97MRGPRX4 | |
| SCHEMBL4585976 | 0.79 | TMEM97 (0.46) | MAOBALDH1A1MAOATMEM97 | |
| SCHEMBL2803707 | 0.79 | TMEM97 (0.55) | ALDH1A1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486974-B2 | Efficient aspirin prodrugs | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH (IE) | 2013-07-16 | — | — | US | disclosed |
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABE (IE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110046182-A1 | EFFICIENT ASPIRIN PRODRUGS | COX15, PTGS1, CYP3A43 | MAOB 1084/4885ALDH1A1 140/4885MAOA 1954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.