SCHEMBL708916

SCHEMBL708916

C=CC(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.46
ALDH1A1 P00352 4/20 0.46
TP53 P04637 3/20 0.46
HIF1A Q16665 3/20 0.46
CYP3A4 P08684 2/20 0.46
HSD17B10 Q99714 1/20 0.46
HPGD P15428 1/20 0.42
THRB P10828 3/20 0.39
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27085680 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1537033 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL347405 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL44451 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536968 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2462848 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL2988873 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536995 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1286343 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1536868 1.00 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 706 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3573461-B1 ANTIMICROBIAL, NON-THROMBOGENIC POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2026-04-22 EP claimed
US-12528966-B2 Coatings P2I LTD (GB) 2026-01-20 US claimed
WO-2025103301-A1 COATING AND PREPARATION METHOD THEREFOR 江苏菲沃泰纳米科技股份有限公司 2025-05-22 WO claimed
EP-3307835-B2 COATINGS P2I LTD (GB) 2025-04-02 EP claimed
US-20240429448-A1 Silicon-Based Energy Storage Devices With Carboxylic Ether, Carboxylic Acid Based Salt, or Acrylate Electrolyte Containing Electrolyte Additives ENEVATE CORP (US) 2024-12-26 US claimed
US-11879024-B1 Soft mold formulations for surface relief grating fabrication with imprinting lithography META PLATFORMS TECHNOLOGIES, LLC (US) 2024-01-23 US claimed
CN-109071966-B Coating layer P2I有限公司 2022-07-22 CN claimed
US-20220145037-A1 METHODS OF PREPARATION OF OMNIPHOBIC SURFACES NUTECH VENTURES (US) 2022-05-12 US claimed
US-11318226-B2 Materials for preparing intraocular lens EYEBRIGHT MEDICAL TECHNOLOGY (BEIJING) CO., LTD. (CN) 2022-05-03 US claimed
EP-3361868-B1 BIOCIDALLY ACTIVE POLYMER COMPOSITIONS LUBRIZOL ADVANCED MAT INC (US) 2021-12-15 EP claimed
US-20140194547-A1 SURFACE MODIFICATION METHOD AND SURFACE-MODIFIED ELASTIC BODY SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-10 US claimed
EP-2752436-A1 Surface modification method and surface-modified elastic body SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-07-09 EP claimed
US-20140128493-A1 SURFACE-MODIFYING METHOD AND ELASTIC BODY WITH MODIFIED SURFACE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2014-05-08 US claimed
US-20130310772-A1 SURFACE MODIFICATION METHOD AND SURFACE-MODIFIED ELASTIC BODY SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-11-21 US claimed
US-20130274367-A1 SURFACE MODIFICATION METHOD, SURFACE-MODIFIED ELASTIC BODY, GASKET FOR INJECTOR, INJECTOR, AND TIRE KYUSHU UNIVERSITY (JP) 2013-10-17 US claimed
US-20100055463-A1 HYDROPHOBIC CARBON BLACK INTERMEDIATE TRANSFER COMPONENTS XEROX CORPORATION (US) 2010-03-04 US claimed
WO-2009082833-A1 FUNCTIONAL FLUORIDE ANTI-BLEED AGENTS WITH REACTIVE GROUPS AN APPLICATION IN ORGANIC BASED CURABLE COMPOSITIONS HENKEL AG & CO. KGAA (DE) 2009-07-09 WO claimed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1303258-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE AstraZeneca AB (SE) 2003-04-23 EP claimed
WO-2002003958-A1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2002-01-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528966-B2 Coatings C9, SDC1, CD59 TSHR 3218/4885ALDH1A1 1446/4885TP53 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.