SCHEMBL1286243

SCHEMBL1286243

O=C(O)C(O)CCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.55
CA12 O43570 1/20 0.53
CA9 Q16790 1/20 0.53
MMP2 P08253 6/20 0.51
MMP9 P14780 6/20 0.51
MAPT P10636 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
NPSR1 Q6W5P4 1/20 0.50
CASP3 P42574 1/20 0.50
RAB9A P51151 1/20 0.50
MMP1 P03956 1/20 0.49
MMP3 P08254 1/20 0.49
MMP13 P45452 1/20 0.49
HDAC1 Q13547 3/20 0.49
HDAC7 Q8WUI4 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1781793 1.00 ALDH1A1 (0.55) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL2640824 0.90 HDAC7 (0.53) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL2640823 0.90 HDAC7 (0.53) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL11686163 0.89 HDAC1 (0.59) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL7080833 0.86 ALDH1A1 (0.58) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL12605262 0.85 ALDH1A1 (0.54) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL30307799 0.83 ALDH1A1 (0.52) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL8897056 0.82 ALDH1A1 (0.70) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL11656910 0.82 ALDH1A1 (0.70) ALDH1A1CA12CA9MMP2MMP9
SCHEMBL8898810 0.82 ALDH1A1 (0.70) ALDH1A1CA12CA9MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122060002-A High-selectivity synthesis method of amikacin sulfate 山东安信制药有限公司 2026-05-19 CN claimed
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
CN-118679637-A Separator for electrochemical device, and electronic device 宁德新能源科技有限公司 2024-09-20 CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
WO-2023184173-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE, ELECTROCHEMICAL DEVICE, AND ELECTRONIC DEVICE 宁德新能源科技有限公司 2023-10-05 WO claimed
WO-2023159610-A1 SEPARATOR FOR ELECTROCHEMICAL DEVICE, ELECTROCHEMICAL DEVICE, AND ELECTRIC APPARATUS 宁德新能源科技有限公司 2023-08-31 WO claimed
CN-115956324-A Separator for electrochemical device, and electricity-using equipment 宁德新能源科技有限公司 2023-04-11 CN claimed
CN-111138505-B Preparation method of amikacin 山东安信制药有限公司 2021-10-08 CN claimed
CN-110642907-B Synthesis method of prazolamide or salt thereof 上海博璞诺科技发展有限公司 2020-11-06 CN claimed
CN-108976267-B Method for synthesizing amikacin 北大方正集团有限公司 2020-10-13 CN claimed
CN-110642907-A Synthesis method of prazolamide or salt thereof 上海博璞诺科技发展有限公司 2020-01-03 CN claimed
CN-110577558-A Preparation method of amikacin 南京济群医药科技股份有限公司 2019-12-17 CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
JP-1275594-A None JP disclosed
US-4001208-A DERIVATIVE OF AN AMINOGLYCOSIDIC ANTIBIOTIC ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYO KAI (JA) 1977-01-04 US disclosed
US-3974137-A ANTIBACTERIAL, ALDEHYDE BLOCKING AGENT BRISTOL-MYERS COMPANY (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885CA12 4479/4885CA9 3829/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885CA12 4479/4885CA9 3829/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS ALDH1A1 3087/4885CA12 4479/4885CA9 3829/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.