Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | CRHBP | P24387 | 1/20 | 0.64 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | RPA1 | P27694 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678639 | 0.92 | MEN1 (0.74) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL14855770 | 0.82 | KCNA5 (0.65) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL7213037 | 0.80 | SMN1; SMN2 (0.58) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL3557458 | 0.79 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL14856070 | 0.78 | TSHR (0.74) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL3557083 | 0.77 | ALDH1A1 (0.55) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL9402809 | 0.77 | ACLY (0.73) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL11246573 | 0.76 | ALDH1A1 (1.00) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL3555027 | 0.76 | SLC16A3 (0.58) | MEN1KMT2AALDH1A1HSD17B10HPGD | |
| SCHEMBL8252530 | 0.75 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947500-B1 | SULFONAMIDE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |