Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12864209 | 0.89 | PGR (0.37) | PDK2PGR | |
| SCHEMBL12864208 | 0.89 | PGR (0.37) | PDK2BACE1ESR1ESR2PGR | |
| SCHEMBL25789256 | 0.88 | KDM4E (0.44) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12864219 | 0.86 | PDK2 (0.46) | PDK2BACE1PGR | |
| SCHEMBL12864193 | 0.85 | PDK2 (0.44) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12864179 | 0.81 | PDK2 (0.34) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL1168040 | 0.79 | MEN1 (0.50) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12879499 | 0.79 | ESR1 (0.43) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12879500 | 0.79 | PGR (0.42) | PDK2PGR | |
| SCHEMBL12879492 | 0.78 | PDK2 (0.54) | PDK2BACE1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361638-B2 | Fluorine derivatives for organic electroluminescence devices | MERCK PATENT GMBH (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | MERCK PATENT GMBH (DE) | 2011-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110037027-A1 | FLUORINE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENCE DEVICES | SLCO4C1, CTCF, AFF2 | KDM4E 1747/4885MEN1 428/4885LMNA 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.