Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 4/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1168040 | 0.90 | MEN1 (0.50) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12879499 | 0.90 | ESR1 (0.43) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12879500 | 0.90 | PGR (0.42) | PDK2GRM5PGR | |
| SCHEMBL12879492 | 0.89 | PDK2 (0.54) | PDK2ADRA2CPGRMAOBCHEK1 | |
| SCHEMBL2606036 | 0.89 | PDK2 (0.52) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12864211 | 0.88 | KDM4E (0.36) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL14665233 | 0.82 | ESR1 (0.35) | KDM4EMEN1LMNAMAPTOPRK1 | |
| SCHEMBL12864208 | 0.80 | PGR (0.37) | PDK2ESR1ESR2GRM5PGR | |
| SCHEMBL12864209 | 0.80 | PGR (0.37) | PDK2GRM5PGR | |
| SCHEMBL12879931 | 0.80 | PDK2 (0.41) | KDM4EMEN1LMNAMAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117835-A1 | ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-06-29 | — | — | WO | disclosed |