Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10392892 | 0.97 | ALDH1A1 (0.61) | ALDH1A1CYP3A4KMT2AHPGDNPC1 | |
| SCHEMBL10366188 | 0.88 | ALDH1A1 (0.58) | ALDH1A1CYP3A4KMT2AHPGDNPC1 | |
| SCHEMBL1286485 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP3A4KMT2ASMN1; SMN2TSHR | |
| SCHEMBL1286469 | 0.83 | ALDH1A1 (0.57) | ALDH1A1CYP3A4KMT2ATSHRMEN1 | |
| SCHEMBL10391870 | 0.82 | ALDH1A1 (0.68) | ALDH1A1CYP3A4KMT2ANPC1RAB9A | |
| SCHEMBL1286436 | 0.81 | CYP3A4 (0.52) | ALDH1A1CYP3A4KMT2ATSHRLMNA | |
| SCHEMBL1283895 | 0.80 | CYP3A4 (0.72) | ALDH1A1CYP3A4KMT2ALMNAPKM | |
| SCHEMBL10634281 | 0.80 | CYP3A4 (0.48) | ALDH1A1CYP3A4KMT2AHPGDNPC1 | |
| SCHEMBL10631803 | 0.80 | CYP3A4 (0.48) | ALDH1A1CYP3A4KMT2AHPGDNPC1 | |
| SCHEMBL1282429 | 0.80 | HPGD (0.40) | ALDH1A1CYP3A4KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443098-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-04-12 | — | — | US | disclosed |
| WO-2010146112-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088660-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | ALDH1A1 1943/4885CYP3A4 19/4885KMT2A 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.