Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PLA2G6 | O60733 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083705 | 0.83 | CYP2C9 (0.42) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10060202 | 0.83 | CYP2C9 (0.42) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL10060203 | 0.83 | CYP2C9 (0.42) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL17695636 | 0.79 | CYP2C9 (0.42) | CYP2C9ALDH1A1LMNAPLA2G6PLA2G4A | |
| SCHEMBL24064823 | 0.78 | CYP2C9 (0.36) | CYP2C9ALDH1A1 | |
| SCHEMBL21013542 | 0.76 | CYP2C9 (0.35) | CYP2C9ALDH1A1MEN1KMT2A | |
| SCHEMBL13962434 | 0.76 | CYP2C9 (0.40) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13840881 | 0.75 | TAAR1 (0.43) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL12426831 | 0.75 | LMNA (0.36) | CYP2C9ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL20182077 | 0.73 | TAAR1 (0.39) | CYP2C9ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884174-B2 | condensation of appropriate anhydrides with appropriate diamines to give amine terminated compounds, then condensed with excess maleic anhydride to yield imide-extended maleimide compounds | DESIGNER MOLECULES, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20080075961-A1 | Imide-linked maleimide and polymaleimide compounds | DESIGNER MOLECULES, INC. | 2008-03-27 | — | — | US | disclosed |