SCHEMBL1083705

SCHEMBL1083705

CCC(c1ccccc1)C1C(=O)OC(=O)C1C

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 6/20 0.42
ALDH1A1 P00352 2/20 0.37
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.30
MIF P14174 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10060202 1.00 CYP2C9 (0.42) CYP2C9ALDH1A1LMNASMN1; SMN2ATM
SCHEMBL10060203 1.00 CYP2C9 (0.42) CYP2C9ALDH1A1LMNASMN1; SMN2ATM
SCHEMBL18133559 0.87 CYP2C9 (0.38) CYP2C9ALDH1A1LMNA
SCHEMBL14407409 0.86 ALDH1A1 (0.32) CYP2C9ALDH1A1LMNASMN1; SMN2ATM
SCHEMBL12866132 0.83 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAPOLBMEN1
SCHEMBL17695636 0.80 CYP2C9 (0.42) CYP2C9ALDH1A1LMNASMN1; SMN2
SCHEMBL18098123 0.80 CYP2C9 (0.40) CYP2C9ALDH1A1LMNAHSD17B10
SCHEMBL13948387 0.78 CYP2C9 (0.36) CYP2C9ALDH1A1LMNASMN1; SMN2NPSR1
SCHEMBL14495989 0.78 CYP2C9 (0.36) CYP2C9ALDH1A1LMNASMN1; SMN2NPSR1
SCHEMBL10331497 0.78 CYP2C9 (0.36) CYP2C9ALDH1A1LMNASMN1; SMN2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239930-A1 FUNCTIONALIZED MALEIC ACID COPOLYMERS FOR ENHANCED BIOACTIVITY UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) 2024-07-18 US disclosed
US-20230399493-A1 FLAME-RETARDANT RESIN COMPOSITION, FLAME-RETARDANT RESIN MOLDED PRODUCT, FLAME-RETARDANT RESIN HOUSING, AND ELECTRONIC DEVICE Konica Minolta, Inc. (JP) 2023-12-14 US disclosed
US-20230312947-A1 DISPERSING AGENT, DISPERSION ELEMENT, INK COMPOSITION, AND METHOD FOR MANUFACTURING SAME NISSIN CHEMICAL INDUSTRY CO., LTD. (JP) 2023-10-05 US disclosed
US-20230303745-A1 COMPOSITION AND METHOD FOR PROVIDING WATER-REPELLENCY HEIQ PTY LTD (AU) 2023-09-28 US disclosed
US-20230303745-A1 COMPOSITION AND METHOD FOR PROVIDING WATER-REPELLENCY HEIQ PTY LTD (AU) 2023-09-28 US disclosed
US-20180208695-A1 UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-07-26 US disclosed
US-10023751-B2 Anti-smudge and anti-graffiti compositions QUEEN'S UNIVERSITY AT KINGSTON (CA) 2018-07-17 US disclosed
US-9920152-B2 UV-absorbing polymers and formulations thereof ISP INVESTMENTS LLC (US) 2018-03-20 US disclosed
US-20170322436-A1 POLYMERIZABLE COMPOSITION, WAVELENGTH CONVERSION MEMBER, BACKLIGHT UNIT, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-11-09 US disclosed
US-20170114173-A1 UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF ISP INVESTMENTS LLC (US) 2017-04-27 US disclosed
US-20100222453-A1 METHOD FOR COLORING BUILDING MATERIALS USING A CATIONIC PIGMENT DISPERSION SUN CHEMICAL CORPORATION (US) 2010-09-02 US disclosed
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS PHARMACHEM LABORATORIES LLC 2010-07-29 US disclosed
US-20090246513-A1 Process for Producing Anti-Fog Coating UNIVERSITé LAVAL (CA) 2009-10-01 US disclosed
US-20090226395-A1 Pharmaceutical compositions of beta-lapachone and beta-lapachone analogs with improved tumor targeting potential ARQULE, INC. (US) 2009-09-10 US disclosed
US-20090148777-A1 Room temperature crosslinkable ion conductive polymer system CIBA CORP. 2009-06-11 US disclosed
US-20090098645-A1 Cell culture article and methods thereof CORNING INCORPORATED 2009-04-16 US disclosed
US-20090025874-A1 Novel Adducts Useful As Cure Components For Anaerobic Curable Compositions HENKEL CORPORATION (US) 2009-01-29 US disclosed
US-7282263-B2 In presence of maleinimide-styrene quaternized polymer as dispersion agent SUN CHEMICAL CORPORATION (US) 2007-10-16 US disclosed
US-20070093610-A1 Method for preparing styrene and maleimide copolymer using super critical fluid LG CHEM, LTD. (KR) 2007-04-26 US disclosed
US-7202304-B2 Anhydride polymers for use as curing agents in epoxy resin-based underfill material INTEL CORPORATION (US) 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170114173-A1 UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF PUF60, UACA, UMPS CYP2C9 1333/4885ALDH1A1 511/4885LMNA 1645/4885
US-20180208695-A1 UV-ABSORBING POLYMERS AND FORMULATIONS THEREOF PUF60, UACA, UMPS CYP2C9 1333/4885ALDH1A1 511/4885LMNA 1645/4885
US-20100189661-A1 POLYMER-BOUND UV ABSORBERS IN PERSONAL CARE COMPOSITIONS CUTA, UACA, LAGE3 CYP2C9 2617/4885ALDH1A1 605/4885LMNA 33/4885
US-20240239930-A1 FUNCTIONALIZED MALEIC ACID COPOLYMERS FOR ENHANCED BIOACTIVITY MDH2, ME1, DDAH1 CYP2C9 1989/4885ALDH1A1 584/4885LMNA 2445/4885
US-20090226395-A1 Pharmaceutical compositions of beta-lapachone and beta-lapachone analogs with improved tumor targeting potential NQO1, KEAP1, DLD CYP2C9 1651/4885ALDH1A1 929/4885LMNA 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.