SCHEMBL12866227

SCHEMBL12866227

CC1(C)/C(=C\c2cccc(OC=O)c2O)N(CCO)c2ccc(Cl)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
PRMT1 Q99873 1/20 0.34
KCNK2 O95069 2/20 0.33
KCNK10 P57789 1/20 0.33
KCNK4 Q9NYG8 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 3/20 0.31
MEN1 O00255 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
PKM P14618 1/20 0.31
IGF1R P08069 1/20 0.31
PTGDR2 Q9Y5Y4 1/20 0.30
TLR2 O60603 1/20 0.30
ERN1 O75460 1/20 0.30
TLR1 Q15399 1/20 0.30
TLR6 Q9Y2C9 1/20 0.30
TP53 P04637 1/20 0.30
CBX7 O95931 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12866281 0.85 LMNA (0.39) ALDH1A1LMNAPRMT1KCNK2KCNK10
SCHEMBL13005243 0.83 LMNA (0.36) ALDH1A1LMNAPRMT1KCNK2KCNK10
SCHEMBL12881948 0.77 PTGDR2 (0.41) ALDH1A1LMNAPRMT1KCNK2KCNK10
SCHEMBL12866224 0.73 PTGDR2 (0.40) ALDH1A1LMNASMN1; SMN2KDM4EMEN1
SCHEMBL7836004 0.68 LMNA (0.46) ALDH1A1LMNAKCNK2KCNK10KCNK4
SCHEMBL12881147 0.66 ALDH1A1 (0.38) ALDH1A1LMNASMN1; SMN2KDM4EMEN1
SCHEMBL12894607 0.66 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2KDM4EMEN1
SCHEMBL30274468 0.66 KCNK2 (0.45) ALDH1A1LMNAPRMT1KCNK2KCNK10
SCHEMBL12880694 0.65 ALDH1A1 (0.35) ALDH1A1LMNASMN1; SMN2KDM4EMEN1
SCHEMBL13005244 0.64 PTGDR2 (0.44) ALDH1A1LMNAPRMT1KCNK2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338701-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-8338700-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-12-25 US disclosed
US-20110030801-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed
US-20110031446-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-02-10 US disclosed