SCHEMBL1286632

SCHEMBL1286632

Nc1ccc2ccc[n+]([O-])c2c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
USP2 O75604 2/20 0.47
RAB9A P51151 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 4/20 0.45
HSD17B10 Q99714 3/20 0.45
CASP1 P29466 4/20 0.43
CASP7 P55210 2/20 0.43
HBB P68871 2/20 0.43
HIF1A Q16665 2/20 0.43
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 4/20 0.42
MAPT P10636 4/20 0.42
HTT P42858 3/20 0.42
LMNA P02545 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
APEX1 P27695 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771699 0.84 ALDH1A1 (0.45) MEN1KMT2AUSP2RAB9ARXFP1
SCHEMBL5894181 0.78 ATM (0.40) MEN1KMT2AUSP2RAB9AALDH1A1
SCHEMBL5782822 0.76 CYP2A6 (0.45) MEN1KMT2AALDH1A1ALOX15TDP1
SCHEMBL1771117 0.76 TNNI3 (0.47) MEN1KMT2ARAB9AALDH1A1CYP3A4
SCHEMBL2107267 0.76 CYP1A2 (0.45) RAB9AALDH1A1KDM4EMAPTHTT
SCHEMBL2088214 0.76 CYP2A6 (0.45) MEN1KMT2AALDH1A1MAPTHTT
SCHEMBL758788 0.76 CYP2A6 (0.45) MEN1KMT2ARXFP1ALDH1A1TDP1
SCHEMBL9531 0.73 ATM (0.48) ATMACHEBCHE
SCHEMBL1000462 0.73 LCK (0.43) MEN1KMT2AALDH1A1CYP3A4HSD17B10
SCHEMBL14742904 0.72 ATM (0.54) MEN1KMT2ARAB9AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN claimed
CN-111732573-B Quinolone acid-aminopyrimidine compound and preparation method and application thereof 复旦大学 2022-09-16 CN claimed
CN-111732573-A Quinolone acid-aminopyrimidine compound and preparation method and application thereof 复旦大学 2020-10-02 CN claimed
US-20150157621-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING THE SAME MARIPOSA HEALTH LTD (AU) 2015-06-11 US claimed
US-8980914-B2 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same MARIPOSA HEALTH LIMITED (AU) 2015-03-17 US claimed
US-20100079635-A1 OPTICAL ELEMENT WAFER MODULE, OPTICAL ELEMENT MODULE, METHOD FOR MANUFACTURING OPTICAL ELEMENT MODULE, ELECTRONIC ELEMENT WAFER MODULE, METHOD FOR MANUFACTURING ELECTRONIC ELEMENT MODULE, ELECTRONIC ELEMENT MODULE AND ELECTRONIC INFORMATION DEVICE SHARP KABUSHIKI KAISHA (JP) 2010-04-01 US claimed
CN-1902057-A Optical recording medium and dye MITSUBISHI CHEM CORP (JP) 2007-01-24 CN claimed
US-20060235045-A1 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-10-19 US claimed
EP-1650191-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD OF TREATMENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE WITH THE SAME DAINIPPON INK AND CHEMICALS, INC. (JP) 2006-04-26 EP claimed
US-6114352-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 2000-09-05 US claimed
EP-0785190-B1 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK & CHEMICALS (JP) 2000-08-16 EP claimed
US-5942521-A Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1999-08-24 US claimed
EP-0785190-A2 Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient DAINIPPON INK AND CHEMICALS, INC. (JP) 1997-07-23 EP claimed
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN disclosed
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN disclosed
CN-119285594-A 7-Aminobenzopyrone or 7-aminoquinolinone compound and application thereof 浙江大学金华研究院 2025-01-10 CN disclosed
EP-0304087-B1 Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent WARNER LAMBERT CO (US) 1994-03-30 EP disclosed
US-4851418-A Naphthyridine antibacterial agents containing an α-amino acid in the side chain of the 7-substituent WARNER-LAMBERT COMPANY (US) 1989-07-25 US disclosed
EP-0304087-A2 Quinolone and naphthyridine antibacterial agents containing an alpha-amino acid in the side chain of the 7-substituent WARNER-LAMBERT COMPANY (US) 1989-02-22 EP disclosed
US-4496481-A REACTING AMINE, COUPLING COMPONENT AND NITRITE;PIGMENTS AND DISPERSE DYES CIBA-GEIGY CORPORATION (US) 1985-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235045-A1 Therapeutic agent for chronic obstructive pulmonary disease and method for treatment for chronic obstructive pulmonary disease with the same ELANE, CFTR, ARG2 MEN1 4882/4885KMT2A 3961/4885USP2 3349/4885
US-20150157621-A1 THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND METHOD FOR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE USING THE SAME ELANE, ARG2, CFTR MEN1 4882/4885KMT2A 3814/4885USP2 3269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.