⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602444 | 0.83 | — | — | |
| SCHEMBL6447288 | 0.81 | — | — | |
| Imidazole Acetic Acid SCHEMBL27340954 | 0.81 | — | — | |
| Imidazole Acetic Acid SCHEMBL9099789 | 0.81 | GABRR1 (0.41) | — | |
| Imidazole Acetic Acid SCHEMBL637983 | 0.81 | — | — | |
| SCHEMBL8227646 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL13437552 | 0.80 | TDP1 (0.33) | — | |
| SCHEMBL27456186 | 0.80 | KDM4E (0.32) | — | |
| SCHEMBL4434828 | 0.79 | — | — | |
| SCHEMBL9238935 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3490983-B1 | DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-02-17 | — | — | EP | disclosed |
| US-9822134-B2 | System for delivering therapeutic agents into living cells and cells nuclei | SABAG-RFA LTD. (IL) | 2017-11-21 | — | — | US | disclosed |
| US-9556210-B2 | System for delivering therapeutic agents into living cells and cells nuclei | SABAG-RFA LTD. (IL) | 2017-01-31 | — | — | US | disclosed |
| US-9376421-B2 | Compounds and methods for myotonic dystrophy therapy | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-06-28 | — | — | US | disclosed |
| US-20160176903-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | SABAG-RFA LTD. (IL) | 2016-06-23 | — | — | US | disclosed |
| US-20160039850-A1 | SYSTEM FOR DELIVERING THERAPEUTIC AGENTS INTO LIVING CELLS AND CELLS NUCLEI | SABAG-RFA LTD. (IL) | 2016-02-11 | — | — | US | disclosed |
| US-9217022-B2 | GLP-1 receptor agonist compounds having stabilized regions | ASTRAZENECA PHARMACEUTICALS LP (US) | 2015-12-22 | — | — | US | disclosed |
| US-9156865-B2 | System for delivering therapeutic agents into living cells and cells nuclei | DELIVERSIR LTD (IL) | 2015-10-13 | — | — | US | disclosed |
| EP-1845973-B1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LTD (GB) | 2015-08-12 | — | — | EP | disclosed |
| US-9072794-B2 | Long-acting glucagon conjugate and pharmaceutical composition comprising the same for the prevention and treatment of obesity | HANMI SCIENCE CO., LTD (KR) | 2015-07-07 | — | — | US | disclosed |
| US-7235627-B2 | Derivatives of GLP-1 analogs | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| US-7235627-B2 | Derivatives of GLP-1 analogs | NOVO NORDISK A/S (DK) | 2007-06-26 | — | — | US | disclosed |
| CN-1934094-A | Diaryl substituted heterocyclic 5-membered ring derivatives | BANYU PHARMA CO LTD (JP) | 2007-03-21 | — | — | CN | disclosed |
| US-7176214-B2 | Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-02-13 | — | — | US | disclosed |
| WO-2006077424-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077428-A1 | PHARMACEUTICAL COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077414-A1 | PYRAZOLE DERIVATIVES FOR THE INHIBITION OF CDK' S AND GSK' S | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077419-A1 | PYRAZOLE DERIVATIVES FOR THE INHIBITION OF CDK' S AND GSK' S | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2006077425-A1 | COMBINATIONS OF PYRAZOLE KINASE INHIBITORS AND FURTHER ANTITUMOR AGENTS | ASTEX THERAPEUTICS LIMITED (GB) | 2006-07-27 | — | — | WO | disclosed |
| WO-2005012256-A1 | 3, 4-DISUBSTITUTED 1H-PYRAZOLE COMPOUNDS AND THEIR USE AS CYCLIN DEPENDENT KINASES (CDK) AND GLYCOGEN SYNTHASE KINASE-3 (GSK-3) MODULATORS | ASTEX THERAPEUTICS LIMITED (GB) | 2005-02-10 | — | — | WO | disclosed |