SCHEMBL128668

SCHEMBL128668

[CH2]C(CC)C(=O)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127780 0.81
SCHEMBL2166892 0.80
SCHEMBL271848 0.80 GAA (0.50)
SCHEMBL5491842 0.79
SCHEMBL28019222 0.77
SCHEMBL28034471 0.77
SCHEMBL27617288 0.77 CA2 (0.59)
SCHEMBL6988170 0.77 L3MBTL1 (0.50)
SCHEMBL128278 0.75 TSHR (0.40)
SCHEMBL6044927 0.75 KMT2A (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100475829-C Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents SCHERING CORP (US) 2009-04-08 CN claimed
US-6982251-B2 Substituted 2-azetidinones useful as hypocholesterolemic agents SCHERING CORPORATION (US) 2006-01-03 US claimed
EP-1510521-A1 Sugar-substituted 2-Azetidinones useful as hypocholesterolemic agents Schering Corporation (US) 2005-03-02 EP claimed
EP-1347987-B1 SUGAR-SUBSTITUTED 2-AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS SCHERING CORP (US) 2004-10-13 EP claimed
CN-1483039-A Sugar-substituted 2-azetidinones as hypocholesterolemic agents ���鹫˾ 2004-03-17 CN claimed
EP-1347987-A1 SUGAR-SUBSTITUTED 2-AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS Schering Corporation (US) 2003-10-01 EP claimed
US-20030105028-A1 Substituted 2-azetidinones useful as hypocholesterolemic agents SCHERING CORPORATION 2003-06-05 US claimed
US-20020137690-A1 Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents SCHERING CORPORATION 2002-09-26 US claimed
WO-2002050090-A1 SUGAR-SUBSTITUTED 2-AZETIDINONES USEFUL AS HYPOCHOLESTEROLEMIC AGENTS SCHERING CORPORATION (US) 2002-06-27 WO claimed
US-5939398-A ANTIATHEROSCLEROSIS AGENTS PFIZER INC. (US) 1999-08-17 US claimed
US-5756470-A ANTICHOLESTEROL AGENTS; CARDIOVASCULAR DISORDERS SCHERING CORPORATION (US) 1998-05-26 US claimed
US-5698526-A ANTICHOLESTEROL AGENT PFIZER INC. (US) 1997-12-16 US claimed
EP-0737203-A1 STEROIDAL GLYCOSIDES PFIZER INC. (US) 1996-10-16 EP claimed
EP-0737202-A1 HYPOCHOLESTEROLEMIC AGENTS PFIZER INC. (US) 1996-10-16 EP claimed
WO-1995018143-A1 HYPOCHOLESTEROLEMIC AGENTS PFIZER INC. (US) 1995-07-06 WO claimed
WO-1995018144-A1 STEROIDAL GLYCOSIDES PFIZER INC. (US) 1995-07-06 WO claimed
US-20230125434-A1 METHOD FOR PRODUCING MONOSULFOXIDE DERIVATIVE KUMIAI CHEMICAL INDUSTRY CO. LTD. (JP) 2023-04-27 US disclosed
EP-4144723-A1 METHOD FOR PRODUCING MONOSULFOXIDE DERIVATIVE Kumiai Chemical Industry Co., Ltd. (JP) 2023-03-08 EP disclosed
EP-0108709-A2 Polyalkyl piperidines CIBA-GEIGY AG (CH) 1984-05-16 EP disclosed
US-4211696-A Disperse monoazo dyestuffs derived from 3,5-dinitro-2-amino thiophene as disazo component and an arylamine coupling component IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-07-08 US disclosed