SCHEMBL12867362

SCHEMBL12867362

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nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APOBEC3A P31941 2/20 0.40
APOBEC3G Q9HC16 2/20 0.40
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
NOS3 P29474 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21937193 1.00 APOBEC3A (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL12867066 1.00 APOBEC3A (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL717531 0.79
SCHEMBL12867077 0.77 APOBEC3A (0.31) APOBEC3AAPOBEC3G
SCHEMBL719071 0.75 ALDH1A1 (0.42) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL1172087 0.71 APOBEC3A (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL14215599 0.71 APOBEC3A (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL24496767 0.67 ALDH1A1 (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL456066 0.67 ALDH1A1 (0.40) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB
SCHEMBL11509455 0.67 APOBEC3A (0.37) APOBEC3AAPOBEC3GALDH1A1LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110040120-A1 PREPARATION OF OSELTAMIVIR PHOSPHATE (TAMIFLU®) AND INTERMEDIATES STARTING FROM D-GLUCOSE OR D-XYLOSE APOTEX PHARMACHEM INC. (CA) 2011-02-17 US disclosed
US-20080009639-A1 Preparation of oseltamivir phosphate (Tamiflu) and intermediates starting from D-glucose or D-xylose APOTEX PHARMACHEM INC. 2008-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110040120-A1 PREPARATION OF OSELTAMIVIR PHOSPHATE (TAMIFLU®) AND INTERMEDIATES STARTING FROM D-GLUCOSE OR D-XYLOSE G6PD, GALE, MGAM APOBEC3A 242/4885APOBEC3G 212/4885ALDH1A1 1478/4885
US-20080009639-A1 Preparation of oseltamivir phosphate (Tamiflu) and intermediates starting from D-glucose or D-xylose G6PD, GALE, MGAM APOBEC3A 337/4885APOBEC3G 298/4885ALDH1A1 1825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.