SCHEMBL1286775

SCHEMBL1286775

O=C(c1ccccc1)c1ccc(O)c(O)c1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
GAA P10253 2/20 0.51
KMT2A Q03164 2/20 0.51
USP2 O75604 1/20 0.51
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
MAPT P10636 4/20 0.46
LMNA P02545 3/20 0.46
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 2/20 0.46
KDM4E B2RXH2 2/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 3/20 0.46
AKR1C3 P42330 1/20 0.46
PDE4A P27815 2/20 0.45
CYP1A2 P05177 1/20 0.45
PGR P06401 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123259 0.87 MEN1 (0.53) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL28492569 0.86 MEN1 (0.51) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL31509453 0.83 SELL (0.57) SMN1; SMN2KDM4EALOX15ALDH1A1AKR1C3
SCHEMBL7026199 0.83 SELL (0.57) SMN1; SMN2KDM4EALOX15ALDH1A1AKR1C3
SCHEMBL27637318 0.83 MAPT (0.53) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL29366285 0.81 HDAC1 (0.66) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL27811794 0.81 HDAC1 (0.66) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL93423 0.81 HDAC1 (0.66) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL10277177 0.81 MEN1 (0.50) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL92724 0.80 AKR1C3 (0.52) MEN1GAAKMT2AUSP2KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117866449-A High-viscosity high-elasticity modified asphalt and preparation method thereof 陕西国琳建设工程有限公司 2024-04-12 CN claimed
EP-1981895-B1 HYDROXYBENZOPHENONE DERIVATIVES BASF SE (DE) 2016-04-27 EP claimed
EP-2313421-B1 LIQUID OXYALKYLENE BRIDGED BIS- AND TRIS-PHOSPHITE ESTER MIXTURES BASF SE (DE) 2012-08-15 EP claimed
EP-1910455-B1 STABILIZATION OF POLYOLEFINS WITH LIQUID TRIS-(MONO-ALKYL)PHENYL PHOSPHITES BASF SE (DE) 2012-08-08 EP claimed
CN-117866449-A High-viscosity high-elasticity modified asphalt and preparation method thereof 陕西国琳建设工程有限公司 2024-04-12 CN disclosed
CN-117866449-A High-viscosity high-elasticity modified asphalt and preparation method thereof 陕西国琳建设工程有限公司 2024-04-12 CN disclosed
EP-1569893-B1 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES BASF SE (DE) 2012-04-11 EP disclosed
EP-1981895-A1 HYDROXYBENZOPHENONE DERIVATIVES Ciba Holding Inc. (CH) 2008-10-22 EP disclosed
WO-2007090832-A1 HYDROXYBENZOPHENONE DERIVATIVES CIBA HOLDING INC. (CH) 2007-08-16 WO disclosed
EP-1569893-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES Ciba SC Holding AG (CH) 2005-09-07 EP disclosed
WO-2004052837-A3 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES CIBA SC HOLDING AG (CH) 2004-09-10 WO disclosed
WO-2004052837-A2 AMINO SUBSTITUTED HYDROXYPHENYL BENZOPHENONE DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-24 WO disclosed
CN-2044076-U Extinction goggles for TV and computer LIN QIXIONG (CN) 1989-09-06 CN disclosed