SCHEMBL1286846

SCHEMBL1286846

O=C(O)c1ccccc1C(=O)OCCSc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.56
▸ TSHR P16473 8/20 0.50
▸ TDP1 Q9NUW8 5/20 0.49
▸ CYP3A4 P08684 3/20 0.49
▸ MAPT P10636 2/20 0.49
▸ RECQL P46063 2/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ KMT2A Q03164 2/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ HPGD P15428 2/20 0.49
▸ KDM4E B2RXH2 1/20 0.49
▸ CYP1A2 P05177 1/20 0.49
▸ CYP2D6 P10635 1/20 0.49
▸ CYP2C9 P11712 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49
▸ HSD17B10 Q99714 1/20 0.49
▸ L3MBTL1 Q9Y468 4/20 0.49
▸ MAPK1 P28482 5/20 0.47
▸ TP53 P04637 1/20 0.47
▸ ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4510397 0.85 ALDH1A1 (0.48) ALDH1A1TSHRTDP1CYP3A4MEN1
SCHEMBL3302489 0.84 ALDH1A1 (0.69) ALDH1A1TSHRTDP1CYP3A4MEN1
SCHEMBL28492073 0.82 ALDH1A1 (0.67) ALDH1A1TSHRTDP1CYP3A4MEN1
SCHEMBL10345933 0.81 TDP1 (0.63) ALDH1A1TSHRTDP1CYP3A4MAPT
SCHEMBL5709795 0.80 TSHR (0.70) ALDH1A1TSHRTDP1CYP3A4SMN1; SMN2
SCHEMBL27446307 0.80 TSHR (0.67) ALDH1A1TSHRTDP1CYP3A4SMN1; SMN2
SCHEMBL1395556 0.79 ALDH1A1 (0.71) ALDH1A1TSHRTDP1CYP3A4MAPT
SCHEMBL11239280 0.79 ALDH1A1 (0.62) ALDH1A1TSHRTDP1CYP3A4MEN1
Ethylene Glycol SCHEMBL8006697 0.79 ALDH1A1 (0.62) ALDH1A1TSHRTDP1CYP3A4MEN1
SCHEMBL29668022 0.79 ALDH1A1 (0.62) ALDH1A1TSHRTDP1CYP3A4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11820844-B2 Charge-modified particles and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-11-21 — — US disclosed
US-11492495-B2 Modified aluminum nitride particles and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-11-08 — — US disclosed
CN-109312201-B Nanoparticle-filled barrier adhesive compositions 3M创新有限公司 2021-12-07 — — CN disclosed
EP-3768794-B1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2021-04-28 — — EP disclosed
EP-3768655-A1 MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME 3M Innovative Properties Company (US) 2021-01-27 — — EP disclosed
EP-3768794-A2 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M Innovative Properties Company (US) 2021-01-27 — — EP disclosed
US-10894903-B2 Nanoparticle filled barrier adhesive compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-01-19 — — US disclosed
US-20210009811-A1 MODIFIED ALUMINUM NITRIDE PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-01-14 — — US disclosed
US-20210002137-A1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2021-01-07 — — US disclosed
CN-111886216-A Modified aluminum nitride particles and method for preparing same 3M创新有限公司 2020-11-03 — — CN disclosed
US-20100033826-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 — — US disclosed
EP-2118149-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M Innovative Properties Company (US) 2009-11-18 — — EP disclosed
WO-2009085926-A2 METHOD OF MAKING ZIRCONIA-CONTAINING NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-07-09 — — WO disclosed
US-7547467-B2 which are dispersed in acrylic polymer to enhance durability and/or refractive index; colloidal titania or zirconia; monophthalate ester (phthalic acid mono-(2-acryloxy-ethyl) ester); a monocarboxylic acid having oxyalkylene groups (2-(2-methoxyethoxy) acetic acid); flat panel displays 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-16 — — US disclosed
US-7547467-B2 which are dispersed in acrylic polymer to enhance durability and/or refractive index; colloidal titania or zirconia; monophthalate ester (phthalic acid mono-(2-acryloxy-ethyl) ester); a monocarboxylic acid having oxyalkylene groups (2-(2-methoxyethoxy) acetic acid); flat panel displays 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-06-16 — — US disclosed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 — — WO disclosed
WO-2008121465-A1 BRIGHTNESS ENHANCING FILM COMPRISING NANOCOMPOSITE STRUCTURE HAVING IMPROVED CRACK RESISTANCE 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-09 — — WO disclosed
WO-2007059228-A1 BRIGHTNESS ENHANCING FILM AND METHOD OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-05-24 — — WO disclosed
US-20070112097-A1 BRIGHTNESS ENHANCING FILM AND METHODS OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 — — US disclosed
US-20070112097-A1 BRIGHTNESS ENHANCING FILM AND METHODS OF SURFACE TREATING INORGANIC NANOPARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2007-05-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210002137-A1 CHARGE-MODIFIED PARTICLES AND METHODS OF MAKING THE SAME PCTP, MBOAT1, CA13 ALDH1A1 3429/4885TSHR 1659/4885TDP1 2116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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