Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | GABRP | O00591 | 1/20 | 0.48 |
| ▸ | GABRD | O14764 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147243 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL20828352 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL147242 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL22001630 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL110580 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL24906952 | 1.00 | ACE (0.58) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| Hydrochloric Acid SCHEMBL4372281 | 0.97 | ACE (0.56) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL11544105 | 0.97 | ACE (0.56) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| Bromide SCHEMBL9180235 | 0.97 | ACE (0.56) | ACEGABRR1AKR1C3AKR1C1LMNA | |
| SCHEMBL11133443 | 0.97 | ACE (0.56) | ACEGABRR1AKR1C3AKR1C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754871-B | Biodegradable block copolyesters based on lactide- (cycloaliphatic-co-aromatic) -lactide | 浙江恒逸石化研究院有限公司 | 2023-06-13 | — | — | CN | claimed |
| CN-113698585-B | Biodegradable glycolide- (alicyclic-co-preparation method of aromatic) -glycolide block copolyesters | 浙江恒逸石化研究院有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-113754871-A | Biodegradable block copolyester based on lactide- (alicyclic-co-aromatic) -lactide | 浙江恒澜科技有限公司 | 2021-12-07 | — | — | CN | claimed |
| CN-113698585-A | Preparation method of biodegradable glycolide- (alicyclic-co-aromatic) -glycolide block copolyester | 浙江恒澜科技有限公司 | 2021-11-26 | — | — | CN | claimed |
| US-8846599-B2 | Branched polyesters with sulfonate groups | BASF SE (DE) | 2014-09-30 | — | — | US | claimed |
| US-20130267547-A1 | PRODRUGS UTILIZING A TRANSPORTER-DIRECTED UPTAKE MECHANISM | VIRGINIA COMMONWEALTH UNIVERSITY | 2013-10-10 | — | — | US | claimed |
| EP-2624869-A2 | PRODRUGS UTILIZING A TRANSPORTER DIRECTED UPTAKE MECHANISM | Virginia Commonwealth University (US) | 2013-08-14 | — | — | EP | claimed |
| WO-2012048204-A2 | PRODRUGS UTILIZING A TRANSPORTER DIRECTED UPTAKE MECHANISM | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2012-04-12 | — | — | WO | claimed |
| WO-2010100199-A1 | FLUCONAZOLE CARBOXYLIC ESTER DERIVATIVES, SYNTHESIS, AND USE IN LONG ACTING FORMULATIONS | SEPS PHARMA N.V. (BE) | 2010-09-10 | — | — | WO | claimed |
| WO-1997016473-A1 | POLYESTERS AND PROCESSES FOR PREPARING SAME | UNION CARBIDE CHEMICALS AND PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-09 | — | — | WO | claimed |
| EP-0543264-B1 | Rewritable thermosensitive recording medium | TOPPAN PRINTING CO LTD (JP) | 1995-05-03 | — | — | EP | claimed |
| US-5362519-A | Polyesters particularly suitable for use in coating compositions which are sprayed with compressed fluids as vicosity reducing agents | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-11-08 | — | — | US | claimed |
| US-5278129-A | Low molecular weight alicyclic dicarboxylic acid | TOPPAN PRINTING CO., LTD. (JP) | 1994-01-11 | — | — | US | claimed |
| EP-0545108-A1 | Polyesters of branched aliphatic diols | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-06-09 | — | — | EP | claimed |
| EP-0543264-A1 | Rewritable thermosensitive recording medium | Toppan Printing Co., Ltd. (JP) | 1993-05-26 | — | — | EP | claimed |
| US-4931509-A | EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES | NIPPON ZEON CO., LTD. (JP) | 1990-06-05 | — | — | US | claimed |
| US-20260137703-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECH LIMITED (GB) | 2026-05-21 | — | — | US | disclosed |
| EP-4720071-A1 | COMPOUNDS FOR THE DEGRADATION OF EGFR KINASE | Beone Medicines I GmbH (CH) | 2026-04-08 | — | — | EP | disclosed |
| US-4650834-A | POLYCARBOXYLIC ACID, QUATERNARY AMMONIUM OR PHOSPHONIUM SALT | NIPPON ZEON CO., LTD. (JP) | 1987-03-17 | — | — | US | disclosed |
| US-4024259-A | 3-Anilino-2,4-diazabicyclo[3.2.1]octenes | AMERICAN HOECHST CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260137703-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | EGFR, KRAS, O60361 | ACE 2160/4885GABRR1 1685/4885AKR1C3 1130/4885 |
| US-20130267547-A1 | PRODRUGS UTILIZING A TRANSPORTER-DIRECTED UPTAKE MECHANISM | SLC27A1, SLC27A2, SLC2A1 | ACE 1835/4885GABRR1 3304/4885AKR1C3 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.