SCHEMBL147242

SCHEMBL147242

O=C(O)[C@H]1CC[C@H](C(=O)O)C1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.58
GABRR1 P24046 1/20 0.53
AKR1C3 P42330 1/20 0.50
AKR1C1 Q04828 1/20 0.50
LMNA P02545 4/20 0.48
PLG P00747 1/20 0.48
PLAT P00750 1/20 0.48
TSHR P16473 3/20 0.48
PMP22 Q01453 2/20 0.48
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL147243 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL20828352 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL1286869 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL22001630 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL110580 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL24906952 1.00 ACE (0.58) ACEGABRR1AKR1C3AKR1C1LMNA
Hydrochloric Acid SCHEMBL4372281 0.97 ACE (0.56) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL11544105 0.97 ACE (0.56) ACEGABRR1AKR1C3AKR1C1LMNA
Bromide SCHEMBL9180235 0.97 ACE (0.56) ACEGABRR1AKR1C3AKR1C1LMNA
SCHEMBL11133443 0.97 ACE (0.56) ACEGABRR1AKR1C3AKR1C1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 498 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113754871-B Biodegradable block copolyesters based on lactide- (cycloaliphatic-co-aromatic) -lactide 浙江恒逸石化研究院有限公司 2023-06-13 CN claimed
CN-113698585-B Biodegradable glycolide- (alicyclic-co-preparation method of aromatic) -glycolide block copolyesters 浙江恒逸石化研究院有限公司 2023-04-28 CN claimed
CN-113754871-A Biodegradable block copolyester based on lactide- (alicyclic-co-aromatic) -lactide 浙江恒澜科技有限公司 2021-12-07 CN claimed
CN-113698585-A Preparation method of biodegradable glycolide- (alicyclic-co-aromatic) -glycolide block copolyester 浙江恒澜科技有限公司 2021-11-26 CN claimed
EP-3609990-B1 POLYMERS AS ADDITIVES FOR FUELS AND LUBRICANTS BASF SE (DE) 2021-10-27 EP claimed
EP-3609990-A1 POLYMERS AS ADDITIVES FOR FUELS AND LUBRICANTS BASF SE (DE) 2020-02-19 EP claimed
US-10179891-B2 Use of branched polyesters based on citric acid as additive in washing compositions, detergents or a formulation for water treatment BASF SE (DE) 2019-01-15 US claimed
EP-2721090-B1 BRANCHED POLYESTERS WITH SULFONATE GROUPS BASF SE (DE) 2015-09-09 EP claimed
EP-2721089-B1 BRANCHED POLYESTERS WITH SULFONATE GROUPS BASF SE (DE) 2015-08-12 EP claimed
US-8846599-B2 Branched polyesters with sulfonate groups BASF SE (DE) 2014-09-30 US claimed
US-20120322950-A1 BRANCHED POLYESTERS WITH SULFONATE GROUPS BASF SE (DE) 2012-12-20 US claimed
US-20120322714-A1 BRANCHED POLYESTERS WITH SULFONATE GROUPS BASF SE (DE) 2012-12-20 US claimed
EP-2155162-B1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME BAUSCH & LOMB (US) 2012-11-21 EP claimed
EP-2155162-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME Bausch & Lomb Incorporated (US) 2010-02-24 EP claimed
US-20080280853-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME BAUSCH & LOMB INCORPORATED 2008-11-13 US claimed
WO-2008137496-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME BAUSCH & LOMB INCORPORATED (US) 2008-11-13 WO claimed
US-20080275000-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME SALIX PHARMACEUTICALS, INC. 2008-11-06 US claimed
EP-0543264-B1 Rewritable thermosensitive recording medium TOPPAN PRINTING CO LTD (JP) 1995-05-03 EP claimed
US-5278129-A Low molecular weight alicyclic dicarboxylic acid TOPPAN PRINTING CO., LTD. (JP) 1994-01-11 US claimed
EP-0543264-A1 Rewritable thermosensitive recording medium Toppan Printing Co., Ltd. (JP) 1993-05-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080275000-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME PDE6D, PDE6H, CA2 ACE 1039/4885GABRR1 262/4885AKR1C3 444/4885
US-20080280853-A1 COMPOSITIONS FOR REDUCING, AMELIORATING, TREATING, OR PREVENTING CONDITION OF DRY EYE AND METHODS OF MAKING AND USING SAME CA2, IDUA, CA6 ACE 489/4885GABRR1 1142/4885AKR1C3 602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.