Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662 | 0.69 | — | — | |
| SCHEMBL17767389 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL5940223 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL2774033 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL4640114 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| Hydrogen Peroxide SCHEMBL28852493 | 0.69 | — | — | |
| SCHEMBL10857351 | 0.69 | — | — | |
| SCHEMBL405938 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL2531259 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL17767367 | 0.69 | TP53 (0.61) | MEN1KMT2AALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359457-B2 | Protein-based conjugates and self-assembled nanostructures | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-06-07 | — | — | US | disclosed |
| US-8916683-B2 | Nanostructured physically-associating hydrogels for injectable, responsive, and tough biomaterials | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-12-23 | — | — | US | disclosed |
| US-20140024722-A1 | Nanostructured Physically-Associating Hydrogels for Injectable, Responsive, and Tough Biomaterials | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-01-23 | — | — | US | disclosed |
| US-20130280782-A1 | PROTEIN-BASED CONJUGATES AND SELF-ASSEMBLED NANOSTRUCTURES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-10-24 | — | — | US | disclosed |
| WO-2012048009-A2 | NANOSTRUCTURED PHYSICALLY-ASSOCIATING HYDROGELS FOR INJECTABLE, RESPONSIVE AND TOUGH BIOMATERIALS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-04-12 | — | — | WO | disclosed |
| US-20110117668-A1 | SELF-POWERED SMART DIAGNOSTIC DEVICES | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024722-A1 | Nanostructured Physically-Associating Hydrogels for Injectable, Responsive, and Tough Biomaterials | MSN, CD44, IGFBP4 | MEN1 2349/4885KMT2A 4158/4885ALDH1A1 4783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.