Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 6/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL542713 | 0.62 | PTGER3 (0.49) | FNTAFNTBMEN1MAPTKMT2A | |
| SCHEMBL7477566 | 0.58 | MEN1 (0.38) | ALDH1A1PARP1CA12CA9SLC6A2 | |
| SCHEMBL25155197 | 0.57 | SLC6A3 (0.53) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL29876796 | 0.57 | SLC6A3 (0.53) | ALDH1A1SLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL25366526 | 0.55 | KDM4E (0.49) | ALDH1A1POLBRXFP1PARP1PDPK1 | |
| Samoquasine A SCHEMBL15954512 | 0.55 | PARP1 (0.57) | ALDH1A1PARP1PDPK1CA12ALOX15 | |
| SCHEMBL30343860 | 0.55 | SLC6A3 (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25155130 | 0.55 | SLC6A3 (0.54) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23709164 | 0.54 | MAPK1 (0.40) | FNTAFNTBALDH1A1PARP1SLC6A2 | |
| SCHEMBL11882237 | 0.54 | CAMK2D (0.50) | POLBPARP1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047630-A2 | N-ALKYL OR N-ARYL SUBSTITUTED GUANIDE AND BIGUANIDE COMPOUNDS AND METHODS OF THEIR USE | TEINTZE MARTIN (US) | 2012-04-12 | — | — | WO | disclosed |