Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1149883 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTMAPK7KMT2AMEN1 | |
| SCHEMBL1149848 | 0.80 | ALDH1A1 (0.69) | ALDH1A1MAPTMAPK7KMT2AMEN1 | |
| SCHEMBL23452267 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL2419793 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPTMAPK7KMT2AMEN1 | |
| SCHEMBL15452407 | 0.74 | HTT (0.71) | ALDH1A1MAPTMAPK7KMT2AMEN1 | |
| SCHEMBL12321357 | 0.74 | ALDH1A1 (0.64) | ALDH1A1MAPTMAPK7KMT2AMEN1 | |
| SCHEMBL10940346 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL18145 | 0.73 | TDP1 (0.63) | ALDH1A1KMT2AGAALMNACYP1A2 | |
| SCHEMBL5568378 | 0.72 | ALDH1A1 (0.51) | ALDH1A1KMT2ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL31114557 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893098-B2 | Pyrrole and pyrazole DAAO inhibitors | SEPRACOR INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20100016397-A1 | Pyrrole and Pyrazole DAAO Inhibitors | SEPRACOR INC. (US) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016397-A1 | Pyrrole and Pyrazole DAAO Inhibitors | DDO, DAO, SRR | ALDH1A1 3634/4885MAPT 1403/4885MAPK7 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.