Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148067 | 0.89 | KDM4E (0.44) | NPC1RAB9AHPGDALDH1A1AR | |
| SCHEMBL1148162 | 0.88 | RAB9A (0.44) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1148206 | 0.87 | NPC1 (0.43) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1147637 | 0.86 | RAB9A (0.43) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1148043 | 0.86 | CNR2 (0.45) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1148217 | 0.83 | RAB9A (0.40) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1148244 | 0.82 | NPC1 (0.41) | NPC1RAB9AHPGDSMN1; SMN2MAPT | |
| SCHEMBL1148268 | 0.82 | TACR3 (0.48) | HPGDCNR2ALDH1A1KMT2ATP53 | |
| SCHEMBL1148267 | 0.81 | MMP1 (0.47) | NPC1RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL1147621 | 0.81 | CYP1A2 (0.42) | SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884103-B2 | such as N-(4-Chloro-phenyl)-2-methyl-2-phenylmethanesulfonylamino-3-(4-[1,2,4]triazol-1-yl-phenoxy)-propionamide, used for controlling or preventing the infestation of plants by phytopathogenic microorganisms, especially fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | SYNGENTA CROP PROTECTION, INC. | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070155748-A1 | N-sulfonyl-alpha-amino-acid derivatives | C3AR1, GLRA1, C5AR1 | NPC1 2365/4885RAB9A 1398/4885HPGD 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.