Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575551 | 0.76 | MAPT (0.56) | PKMMAPTALDH1A1NPBWR1MCHR1 | |
| SCHEMBL31455781 | 0.76 | MEN1 (0.55) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL1835292 | 0.76 | MEN1 (0.55) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL15973849 | 0.75 | NOS1 (0.55) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14399403 | 0.74 | MAPT (0.45) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5905840 | 0.74 | KMT2A (0.70) | MAPTPOLBSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL15986775 | 0.74 | MAPT (0.45) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL4873349 | 0.74 | MAPT (0.45) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5380629 | 0.74 | CYP1A2 (0.47) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL3096453 | 0.74 | MAPT (0.45) | PKMMAPTPOLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884242-B2 | N1-(6-{[3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl]methyl}-2-methylpyridin-3-yl)-3-chloro-N2-[(1S)-1-methyl-2-(methylthio)ethyl]phthalamide; pesticide; nematocide | BAYER CROPSCIENCE AG (DE) | 2011-02-08 | — | — | US | disclosed |
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | BAYER CROPSCIENCE AG (DE) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023752-A1 | N-Heterocyclylphthaldiamides as Insecticides | DDT, NQO2, NIT2 | PKM 2479/4885MAPT 4220/4885POLB 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.