SCHEMBL4873349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29394347	1.00	MAPT (0.45)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL31456058	0.81	LOXL2 (0.52)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL14399403	0.81	MAPT (0.45)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL5380629	0.81	CYP1A2 (0.47)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL15986775	0.81	MAPT (0.45)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL1126175	0.81	ADRA2A (0.49)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL3096453	0.81	MAPT (0.45)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL28900871	0.79	ADRA2A (0.47)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL8200767	0.78	POLB (0.49)	MAPTALDH1A1GAARAB9ANPC1
	SCHEMBL7075509	0.78	CYP2C19 (0.48)	MAPTALDH1A1GAARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.