Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426783 | 0.77 | SLC1A3 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1USP2 | |
| SCHEMBL11005597 | 0.76 | TP53 (0.35) | SLC7A5 | |
| SCHEMBL2031755 | 0.74 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL571632 | 0.74 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL17667384 | 0.74 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| Isoleucine SCHEMBL1255582 | 0.73 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Isoleucine SCHEMBL8868 | 0.73 | — | — | |
| Isoleucine SCHEMBL20340795 | 0.73 | — | — | |
| Isoleucine SCHEMBL8043620 | 0.73 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Bicarbonate SCHEMBL8039500 | 0.73 | GABRP (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012048013-A2 | PHOSPHORODIAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INJECTIONS | INHIBITEX, INC. (US) | 2012-04-12 | — | — | WO | disclosed |