Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990665 | 0.77 | NCF1 (0.37) | — | |
| SCHEMBL15691793 | 0.77 | NCF1 (0.37) | — | |
| SCHEMBL17464281 | 0.75 | — | — | |
| SCHEMBL13286237 | 0.73 | GBA1 (0.38) | — | |
| SCHEMBL14071752 | 0.73 | GBA1 (0.38) | — | |
| SCHEMBL10226710 | 0.72 | — | — | |
| SCHEMBL25530706 | 0.72 | — | — | |
| SCHEMBL20289190 | 0.72 | HRH3 (0.31) | — | |
| SCHEMBL10226702 | 0.72 | — | — | |
| SCHEMBL15929732 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011012540-A1 | TRICYCLIC INHIBITORS OF JAK | F. HOFFMANN-LA ROCHE AG (CH) | 2011-02-03 | — | — | WO | disclosed |