Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14071752 | 1.00 | GBA1 (0.38) | GBA1SMN1; SMN2OPRM1OPRK1OPRL1 | |
| SCHEMBL19087105 | 0.81 | GBA1 (0.41) | GBA1 | |
| SCHEMBL13286238 | 0.80 | GBA1 (0.38) | GBA1SMN1; SMN2OPRM1OPRK1OPRL1 | |
| SCHEMBL27391281 | 0.78 | GBA1 (0.37) | GBA1SMN1; SMN2OPRM1OPRK1OPRL1 | |
| SCHEMBL18542747 | 0.76 | SMN1; SMN2 (0.39) | GBA1SMN1; SMN2HSD11B1 | |
| SCHEMBL12938791 | 0.76 | SMN1; SMN2 (0.39) | GBA1SMN1; SMN2HSD11B1 | |
| SCHEMBL23475112 | 0.76 | GBA1 (0.46) | GBA1SMN1; SMN2 | |
| SCHEMBL25501186 | 0.76 | GBA1 (0.46) | GBA1SMN1; SMN2 | |
| SCHEMBL15691793 | 0.75 | NCF1 (0.37) | GBA1 | |
| SCHEMBL22648343 | 0.75 | GBA1 (0.40) | GBA1SMN1; SMN2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010084152-A1 | NOVEL BICYCLIC ANTIBIOTICS | BASILEA PHARMACEUTICA AG (CH) | 2010-07-29 | — | — | WO | disclosed |