Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CXCR3 | P49682 | 12/20 | 0.59 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287438 | 0.88 | MEN1 (0.59) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287435 | 0.85 | MEN1 (0.66) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287403 | 0.85 | MEN1 (0.62) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287401 | 0.85 | MEN1 (0.62) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287468 | 0.85 | MEN1 (0.64) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287263 | 0.84 | POLB (0.69) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287273 | 0.83 | MEN1 (0.89) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287545 | 0.83 | MEN1 (0.59) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287255 | 0.81 | MEN1 (0.62) | MEN1KMT2APOLBCXCR3TAS2R14 | |
| SCHEMBL1287378 | 0.81 | MEN1 (0.73) | MEN1KMT2APOLBCXCR3TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |