Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.63 |
| ▸ | TAS2R14 | Q9NYV8 | 5/20 | 0.63 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 1/20 | 0.54 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.54 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287503 | 0.91 | TAS2R14 (0.71) | POLBMEN1KMT2ACXCR3TAS2R14 | |
| SCHEMBL1169742 | 0.91 | TP53 (0.79) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL1287492 | 0.91 | PSEN1 (0.58) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL1287296 | 0.88 | MAPT (0.54) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL1287273 | 0.88 | MEN1 (0.89) | POLBMEN1KMT2ATP53CXCR3 | |
| SCHEMBL1169305 | 0.86 | TP53 (0.70) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL1287403 | 0.86 | MEN1 (0.62) | POLBMEN1KMT2AMAPTTP53 | |
| SCHEMBL1287378 | 0.86 | MEN1 (0.73) | POLBMEN1KMT2ATP53CXCR3 | |
| SCHEMBL1287414 | 0.86 | TAS2R14 (0.69) | POLBMEN1KMT2ACXCR3TAS2R14 | |
| SCHEMBL1287336 | 0.84 | MEN1 (0.62) | POLBMEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |