Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.89 |
| ▸ | POLB | P06746 | 1/20 | 0.89 |
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.81 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.81 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 2/20 | 0.60 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287301 | 0.94 | MEN1 (1.00) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287314 | 0.94 | MEN1 (0.77) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287284 | 0.91 | MEN1 (0.73) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287378 | 0.91 | MEN1 (0.73) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287496 | 0.90 | MEN1 (0.93) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1168758 | 0.90 | TAS2R14 (1.00) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1279324 | 0.90 | TAS2R14 (1.00) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287315 | 0.88 | MEN1 (0.70) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287407 | 0.88 | TAS2R14 (0.81) | MEN1KMT2APOLBTAS2R14CXCR3 | |
| SCHEMBL1287395 | 0.88 | MEN1 (0.69) | MEN1KMT2APOLBTAS2R14CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |