Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EEF2K | O00418 | 5/20 | 0.72 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388183 | 1.00 | EEF2K (0.72) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL15388076 | 0.84 | ALDH1A1 (0.56) | EEF2KKCNA5ALDH1A1L3MBTL1ATM | |
| SCHEMBL1287380 | 0.84 | ALDH1A1 (0.56) | EEF2KKCNA5ALDH1A1L3MBTL1ATM | |
| SCHEMBL28408144 | 0.84 | EEF2K (1.00) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL15387938 | 0.83 | ALDH1A1 (0.56) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL1287422 | 0.83 | ALDH1A1 (0.56) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL1287300 | 0.81 | MAPT (0.57) | KCNA5CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL1287270 | 0.81 | MAPT (0.57) | KCNA5CYP3A4CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL28621232 | 0.80 | EEF2K (0.61) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL28616437 | 0.78 | ALDH1A1 (0.59) | EEF2KKCNA5CYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | BACE1, BACE2, GSAP | EEF2K 3689/4885KCNA5 1128/4885CYP3A4 3517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.