Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EEF2K | O00418 | 3/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15388076 | 1.00 | ALDH1A1 (0.56) | ALDH1A1ATML3MBTL1EEF2KKCNA5 | |
| SCHEMBL1287457 | 0.85 | UTS2R (0.54) | ALDH1A1KCNA5KMT2AMEN1 | |
| SCHEMBL15388077 | 0.85 | UTS2R (0.54) | ALDH1A1KCNA5KMT2AMEN1 | |
| SCHEMBL1287300 | 0.85 | MAPT (0.57) | ALDH1A1ATML3MBTL1KCNA5KMT2A | |
| SCHEMBL1287270 | 0.85 | MAPT (0.57) | ALDH1A1ATML3MBTL1KCNA5KMT2A | |
| SCHEMBL1287344 | 0.84 | EEF2K (0.72) | ALDH1A1ATML3MBTL1EEF2KKCNA5 | |
| SCHEMBL15388183 | 0.84 | EEF2K (0.72) | ALDH1A1ATML3MBTL1EEF2KKCNA5 | |
| SCHEMBL15387917 | 0.84 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1EEF2KKCNA5 | |
| SCHEMBL15387918 | 0.84 | ALDH1A1 (0.53) | ALDH1A1ATML3MBTL1EEF2KKCNA5 | |
| SCHEMBL1287475 | 0.81 | MAPT (0.58) | ALDH1A1ATML3MBTL1EEF2KKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-11-21 | — | — | US | disclosed |
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130310384-A1 | Sulfonamide-Containing Compounds | BACE1, BACE2, GSAP | ALDH1A1 3025/4885ATM 3838/4885L3MBTL1 3763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.