Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 18/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.62 |
| ▸ | PTGES | O14684 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287314 | 0.94 | MEN1 (0.77) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1287284 | 0.91 | MEN1 (0.73) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1287316 | 0.90 | TAS2R14 (0.76) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1279281 | 0.90 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1169654 | 0.90 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1287273 | 0.88 | MEN1 (0.89) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1287322 | 0.87 | MEN1 (0.65) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1287426 | 0.87 | MEN1 (0.65) | TAS2R14MEN1KMT2APOLBCXCR3 | |
| SCHEMBL1615817 | 0.86 | TAS2R14 (1.00) | TAS2R14MEN1KMT2ACXCR3PTGES | |
| SCHEMBL1287359 | 0.85 | TAS2R14 (0.83) | TAS2R14MEN1KMT2APOLBCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012047926-A2 | SULFONAMIDE-CONTAINING COMPOUNDS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2012-04-12 | — | — | WO | disclosed |