Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12874801 | 0.90 | PTGER1 (0.37) | PTGER1ALDH1A1PKMKDM4ELMNA | |
| SCHEMBL12874797 | 0.89 | CCR5 (0.40) | PTGER1TAAR1ALDH1A1LMNAKMT2A | |
| SCHEMBL1163144 | 0.85 | HTR2A (0.48) | PTGER1TAAR1MAPK14KDM1A | |
| SCHEMBL1163138 | 0.79 | HTR6 (0.53) | PTGER1CHRM1KMT2A | |
| SCHEMBL1163695 | 0.76 | HTR2A (0.42) | PTGER1KDM4EKMT2A | |
| SCHEMBL3804876 | 0.76 | HTR2A (0.48) | TAAR1KDM1A | |
| SCHEMBL1163366 | 0.75 | HTR2A (0.43) | PTGER1KMT2A | |
| SCHEMBL16509893 | 0.74 | HTR2A (0.47) | TAAR1KDM1A | |
| SCHEMBL3806838 | 0.74 | HTR2A (0.47) | TAAR1KDM1A | |
| SCHEMBL1163361 | 0.74 | HTR2A (0.42) | PTGER1KDM1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019738-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |