Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1163178 | 0.85 | HTR6 (0.54) | CHRM1SMN1; SMN2SLC5A1SLC5A2HTR6 | |
| SCHEMBL12874796 | 0.75 | HRH3 (0.45) | HSP90AA1LMNATAAR1HSP90B1 | |
| SCHEMBL12874302 | 0.72 | PTGER1 (0.39) | CHRM1SMN1; SMN2LMNATAAR1 | |
| SCHEMBL22416064 | 0.70 | CHRM1 (0.83) | CHRM1SMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL16341842 | 0.70 | CHRM1 (0.78) | CHRM1SMN1; SMN2HDAC1HDAC2HDAC6 | |
| SCHEMBL16341817 | 0.68 | CHRM1 (1.00) | CHRM1SMN1; SMN2LMNA | |
| SCHEMBL12874801 | 0.68 | PTGER1 (0.37) | CHRM1SMN1; SMN2LMNA | |
| SCHEMBL1163260 | 0.68 | HTR2A (0.43) | CHRM1HTR6HDAC1HDAC8HDAC6 | |
| SCHEMBL16341848 | 0.68 | CHRM1 (0.81) | CHRM1SMN1; SMN2LMNAPOLB | |
| SCHEMBL16341768 | 0.67 | CHRM1 (0.72) | CHRM1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019738-A1 | COMPOUNDS AND METHODS OF USE THEREOF | GALENEA CORPORATION (US) | 2011-02-17 | — | — | WO | disclosed |