Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1164515 | 0.99 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CHRNA7MEN1 | |
| Hydrochloric Acid SCHEMBL1164513 | 0.99 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3CHRNA7MEN1 | |
| SCHEMBL16147114 | 0.82 | EPHX2 (0.61) | MEN1KMT2ACA1CA2EPHX2 | |
| SCHEMBL3969710 | 0.82 | PARP10 (0.64) | SLC6A4SLC6A2SLC6A3CHRNA7KMT2A | |
| SCHEMBL23536781 | 0.80 | CA1 (0.53) | MEN1KMT2ACA1CA2EPHX2 | |
| SCHEMBL23594155 | 0.80 | CA1 (0.53) | MEN1KMT2ACA1CA2EPHX2 | |
| SCHEMBL12345375 | 0.80 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3CHRNA7MEN1 | |
| SCHEMBL8339652 | 0.80 | PARP10 (0.60) | CA1CA2EPHX2MAPTFAAH | |
| SCHEMBL2683190 | 0.79 | KDM4E (0.50) | CHRNA7MEN1KMT2ACA1CA2 | |
| SCHEMBL10243417 | 0.79 | KDM4E (0.50) | CHRNA7MEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011021645-A1 | BICYCLIC UREA DERIVATIVE OR PHARMACOLOGICALLY PERMITTED SALT THEREOF | 大日本住友製薬株式会社 (JP) | 2011-02-24 | — | — | WO | disclosed |