Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1436418 | 0.85 | POLB (0.64) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL881352 | 0.84 | ALDH1A1 (0.52) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL14146273 | 0.83 | POLB (0.43) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL23792950 | 0.83 | TSHR (0.50) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL20982590 | 0.83 | CA12 (0.50) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL7358447 | 0.83 | CA12 (0.69) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL6939685 | 0.83 | TSHR (0.71) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL10381364 | 0.81 | FABP4 (0.49) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL1346383 | 0.81 | POLB (0.49) | POLBCASP6TSHRCA12CA1 | |
| SCHEMBL28057530 | 0.80 | CA1 (0.69) | TSHRCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016468-A1 | BENZYL PIPERIDINE COMPOUND | 大日本住友製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |