SCHEMBL12876994

SCHEMBL12876994

Bc1ccc(CC2CCN(C)CC2)cc1OCCOC

nearest known ligand 0.52

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 18/20 0.52
HTR1A P08908 17/20 0.49
CYP2D6 P10635 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9943151 0.85 SLC6A4 (0.72) SLC6A4HTR1ACYP2D6
SCHEMBL12876993 0.81 SCN9A (0.44) SLC6A4HTR1ACYP2D6
SCHEMBL11957259 0.78 SLC6A4 (0.54) SLC6A4HTR1ACYP2D6
SCHEMBL12876798 0.76 HTR1A (0.81) SLC6A4HTR1ACYP2D6
SCHEMBL25758964 0.76 ABCB1 (0.61) SLC6A4HTR1ACYP2D6
SCHEMBL1911910 0.73 ABCB1 (0.49) SLC6A4HTR1ACYP2D6
SCHEMBL12876990 0.72 CBFB (0.39) SLC6A4
SCHEMBL12876995 0.72 SLC6A4 (0.38) SLC6A4
SCHEMBL1344471 0.71 SLC6A4 (0.53) SLC6A4HTR1ACYP2D6
SCHEMBL1346749 0.71 SLC6A4 (0.54) SLC6A4HTR1ACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011016468-A1 BENZYL PIPERIDINE COMPOUND 大日本住友製薬株式会社 (JP) 2011-02-10 WO disclosed