Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12876990 | 0.83 | CBFB (0.39) | SLC6A4KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL13192014 | 0.80 | L3MBTL1 (0.51) | SLC6A4KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL26024874 | 0.76 | L3MBTL1 (0.38) | KMT2AL3MBTL1KDM4EHTTPOLB | |
| SCHEMBL12876994 | 0.72 | SLC6A4 (0.52) | SLC6A4 | |
| SCHEMBL12876992 | 0.71 | POLB (0.49) | KMT2ACA2KDM4EHTTPOLB | |
| SCHEMBL13634485 | 0.69 | L3MBTL1 (0.50) | KMT2AL3MBTL1MEN1NPC1CA2 | |
| SCHEMBL13185202 | 0.68 | BIRC5 (0.46) | SLC6A4KMT2AL3MBTL1MEN1NPC1 | |
| SCHEMBL6943325 | 0.68 | KDM4E (0.51) | KMT2AL3MBTL1MEN1NPC1CA2 | |
| SCHEMBL27442665 | 0.68 | CA2 (0.71) | CA2KDM4EPOLBATMMAPT | |
| SCHEMBL1057005 | 0.67 | NPC1 (0.47) | SLC6A4KMT2AL3MBTL1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011016468-A1 | BENZYL PIPERIDINE COMPOUND | 大日本住友製薬株式会社 (JP) | 2011-02-10 | — | — | WO | disclosed |