SCHEMBL12878422

SCHEMBL12878422

O=S(=O)(NS(=O)(=O)C(F)(F)S(=O)(=O)C1CCCCC1)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 3/20 0.35
PTGS2 P35354 3/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10211278 0.79 PTGS1 (0.35) PTGS1PTGS2CA1CA2
SCHEMBL30199182 0.75 CA1 (0.33) CA1CA2
SCHEMBL21010745 0.70 PTGS1 (0.41) PTGS1PTGS2CA1CA2
SCHEMBL37874 0.69 CA2 (0.56) CA1CA2
SCHEMBL4457449 0.69 CA2 (0.56) CA1CA2
SCHEMBL12332410 0.68 CA1 (0.32) CA1CA2
SCHEMBL18195856 0.68 CA1 (0.45) PTGS1PTGS2CA1CA2
SCHEMBL18195857 0.68 CA1 (0.45) PTGS1PTGS2CA1CA2
SCHEMBL1697213 0.67 PDK1 (0.33) CA1
SCHEMBL23886640 0.67 CA2 (0.53) PTGS1PTGS2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110045413-A1 RESIST COMPOSITION FOR NEGATIVE TONE DEVELOPMENT AND PATTERN FORMING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2011-02-24 US disclosed