Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | APLNR | P35414 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675669 | 0.82 | FYN (0.35) | SLC6A4HTR2AKCNH2ALDH1A1IDO1 | |
| SCHEMBL8340513 | 0.82 | SLC6A4 (0.47) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL4510419 | 0.82 | ALDH1A1 (0.53) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL473882 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL19534980 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL7667135 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL3086920 | 0.80 | SLC6A4 (0.46) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL2430164 | 0.80 | HTR2B (0.49) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL5753110 | 0.80 | ALDH1A1 (0.54) | SLC6A4HTR2AKCNH2APLNRSLC6A2 | |
| SCHEMBL5975064 | 0.80 | IDO1 (0.55) | SLC6A4HTR2AKCNH2APLNRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020615-A1 | NOVEL FXR (NR1H4 ) BINDING AND ACTIVITY MODULATING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2011-02-24 | — | — | WO | disclosed |