Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879071 | 0.90 | NR1H4 (0.36) | NR1H4HPGD | |
| SCHEMBL18724951 | 0.83 | TAAR1 (0.42) | — | |
| SCHEMBL12879281 | 0.83 | NR1H4 (0.31) | NR1H4 | |
| SCHEMBL12879002 | 0.83 | NR1H4 (0.33) | NR1H4 | |
| SCHEMBL12879262 | 0.78 | NR1H4 (0.41) | NR1H4 | |
| SCHEMBL12879269 | 0.76 | NR1H4 (0.42) | NR1H4 | |
| SCHEMBL12879170 | 0.76 | NR1H4 (0.37) | NR1H4 | |
| SCHEMBL12879010 | 0.75 | NR1H4 (0.57) | NR1H4 | |
| SCHEMBL14215909 | 0.74 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL12879085 | 0.74 | NR1H4 (0.58) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011020615-A1 | NOVEL FXR (NR1H4 ) BINDING AND ACTIVITY MODULATING COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2011-02-24 | — | — | WO | disclosed |