Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2749706 | 0.83 | KCNH2 (0.59) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL1200313 | 0.82 | HPGD (0.80) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL17900443 | 0.80 | HPGD (0.65) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL532885 | 0.80 | LMNA (0.78) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL12395476 | 0.80 | SLC10A6 (0.69) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL1199735 | 0.79 | LMNA (1.00) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL1200311 | 0.78 | KCNH2 (0.66) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL1199098 | 0.78 | LMNA (0.78) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL2750244 | 0.78 | LMNA (0.78) | HPGDTSHRLMNAKCNH2SLC10A6 | |
| SCHEMBL1199804 | 0.78 | HPGD (0.78) | HPGDTSHRLMNAKCNH2SLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110028469-A1 | Thiphene-2-Carboxamide Derivatives As Modulators of CCR9 Receptor | ANDERSON ERIC C | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028469-A1 | Thiphene-2-Carboxamide Derivatives As Modulators of CCR9 Receptor | CCR9, CCR1, CCR10 | HPGD 2182/4885TSHR 518/4885LMNA 4182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.