Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | VHL | P40337 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136387 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL6136389 | 0.84 | ALDH1A1 (0.51) | ALDH1A1GAAMAPTCYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20677194 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL28819828 | 0.83 | MAPT (0.46) | ALDH1A1GAAMAPTCYP19A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20677195 | 0.83 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTCYP19A1SMN1; SMN2 | |
| SCHEMBL7674546 | 0.81 | POLB (0.67) | ALDH1A1MAPTHDAC6POLBHPGD | |
| SCHEMBL24011470 | 0.80 | CYP1A2 (0.64) | GAAMAPTPOLBHPGDMAPK8 | |
| SCHEMBL14279030 | 0.80 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTRAB9ANAMPT | |
| SCHEMBL12890313 | 0.80 | SMN1; SMN2 (0.54) | ALDH1A1GAASMN1; SMN2HDAC6NAMPT | |
| SCHEMBL12839870 | 0.79 | HPGD (0.64) | ALDH1A1GAASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255915-A1 | PET RADIOTRACERS | NORDBERG AGNETA (SE) | 2022-12-08 | — | — | WO | disclosed |
| US-20110028509-A1 | Sulfonamides | MERCK SERONO SA (CH) | 2011-02-03 | — | — | US | disclosed |
| US-20100105683-A1 | COMPOUNDS USEFUL FOR INHIBITING CHK1 | KEEGAN KATHLEEN S | 2010-04-29 | — | — | US | disclosed |
| US-7608618-B2 | Urea or thiourea substituted 1,4-pyrazine compounds useful as anti-cancer agents and for inhibiting Chk1 | ICOS CORPORATION (US) | 2009-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105683-A1 | COMPOUNDS USEFUL FOR INHIBITING CHK1 | CHEK1, PCNA, CHEK2 | ALDH1A1 3047/4885GAA 1301/4885MAPT 3233/4885 |
| US-20110028509-A1 | Sulfonamides | CXCR3, CXCR2, CXCR1 | ALDH1A1 716/4885GAA 3909/4885MAPT 4698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.