Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | F12 | P00748 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12882191 | 0.84 | KMT2A (0.51) | KMT2ANPC1RAB9AKDM4EKLK7 | |
| SCHEMBL12882215 | 0.82 | CES2 (0.42) | KMT2A | |
| SCHEMBL4320783 | 0.79 | KMT2A (0.49) | HSD17B10KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL1224575 | 0.76 | CES2 (0.36) | KMT2AMAPTTSHR | |
| SCHEMBL12883793 | 0.73 | EP300 (0.38) | KMT2AMAPK1 | |
| SCHEMBL12883780 | 0.71 | DCK (0.42) | KMT2ANPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL1739594 | 0.71 | ALB (0.38) | — | |
| SCHEMBL12882192 | 0.70 | KMT2A (0.47) | KMT2AKDM4EMAPTPOLBTHRB | |
| SCHEMBL6880479 | 0.69 | KMT2A (0.52) | KMT2ANPC1RAB9AKDM4EMAPK1 | |
| SCHEMBL1224879 | 0.68 | EP300 (0.46) | HSD17B10KMT2AKDM4EPOLBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519512-B1 | N1-ACYL- 5-FLUOROPYRIMIDINONE DERIVATIVES | ADAMA MAKHTESHIM LTD (IL) | 2019-03-20 | — | — | EP | disclosed |
| US-8470839-B2 | N1-acyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES, LLC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-8470839-B2 | N1-acyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES, LLC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20110034490-A1 | N1-acyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
| WO-2011017538-A1 | N1-ACYL-5-FLUOROPYRIMIDINONE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034490-A1 | N1-acyl-5-fluoropyrimidinone derivatives | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034490-A1 | N1-acyl-5-fluoropyrimidinone derivatives | NANP, NAT1, AKR7A2 | HSD17B10 1706/4885KMT2A 1286/4885NPC1 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.