Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13480382 | 0.96 | FFAR4 (0.39) | PDE2AEPHX2MCHR1SLC7A5TRPV1 | |
| SCHEMBL16326079 | 0.96 | FFAR4 (0.39) | PDE2AEPHX2MCHR1SLC7A5TRPV1 | |
| SCHEMBL16325873 | 0.89 | FFAR4 (0.35) | PDE2AEPHX2MCHR1SLC7A5TRPV1 | |
| SCHEMBL18034048 | 0.89 | FFAR4 (0.35) | PDE2AEPHX2MCHR1SLC7A5FFAR4 | |
| SCHEMBL18034090 | 0.88 | MCHR1 (0.34) | PDE2AEPHX2MCHR1SLC7A5HCRTR1 | |
| SCHEMBL16325975 | 0.88 | ALOX5AP (0.40) | PDE2AEPHX2MCHR1SLC7A5FFAR4 | |
| SCHEMBL16325930 | 0.86 | PPIB (0.37) | PDE2AEPHX2MCHR1FFAR4GRM2 | |
| SCHEMBL12889527 | 0.85 | TAS1R3 (0.35) | PDE2AEPHX2TRPV1FFAR4GRM2 | |
| SCHEMBL14366208 | 0.85 | SLC6A2 (0.38) | — | |
| SCHEMBL14366226 | 0.85 | FFAR4 (0.32) | PDE2AEPHX2MCHR1SLC7A5FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888519-B2 | Liquid crystals; using metastasis catalysts; reduction, hydrogenation | MERCK PATENT GESELLSCHAFT (DE) | 2011-02-15 | — | — | US | disclosed |
| US-7314943-B2 | Pyran derivatives containing an exocyclic double bond | MERCK PATENT GMBH (DE) | 2008-01-01 | — | — | US | disclosed |