Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.34 |
| ▸ | PNLIP | P16233 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889490 | 0.85 | PDE2A (0.38) | — | |
| SCHEMBL12889527 | 0.82 | TAS1R3 (0.35) | SLC6A4EPAS1SCN9A | |
| SCHEMBL12889463 | 0.82 | GRM2 (0.43) | CNR2 | |
| SCHEMBL16326079 | 0.82 | FFAR4 (0.39) | — | |
| SCHEMBL13480382 | 0.82 | FFAR4 (0.39) | — | |
| SCHEMBL17547990 | 0.80 | HSD11B1 (0.32) | SLC6A2SLC6A4SLC6A3SCN9A | |
| SCHEMBL10027434 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL16325796 | 0.79 | GRM2 (0.41) | — | |
| SCHEMBL2741538 | 0.79 | FFAR4 (0.37) | EPAS1 | |
| SCHEMBL18503356 | 0.79 | FFAR4 (0.37) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291367-B2 | Liquid-crystalline compounds | MERCK PATENT GMBH (DE) | 2007-11-06 | — | — | US | disclosed |