Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15603972 | 0.90 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL12889566 | 0.89 | — | — | |
| SCHEMBL12889486 | 0.89 | — | — | |
| SCHEMBL12889548 | 0.87 | FFAR4 (0.39) | SCN10A | |
| SCHEMBL2741546 | 0.86 | CYP11B1 (0.34) | ANPEPCYP11B1CYP11B2 | |
| SCHEMBL12929135 | 0.86 | CYP11B1 (0.34) | ANPEPCYP11B1CYP11B2 | |
| SCHEMBL12889559 | 0.86 | ALOX5AP (0.36) | — | |
| SCHEMBL12889536 | 0.85 | HTR2A (0.33) | SCN10A | |
| SCHEMBL12889531 | 0.83 | — | — | |
| SCHEMBL12829122 | 0.82 | GPR3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888519-B2 | Liquid crystals; using metastasis catalysts; reduction, hydrogenation | MERCK PATENT GESELLSCHAFT (DE) | 2011-02-15 | — | — | US | disclosed |